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Antigenic Specificity | NCF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of T47D cell lysate using NCF1 antibody. The phagocytic NADPH oxidase is a multiprotein enzyme that catalyzes the reduction of oxygen to superoxide in response to pathogenic invasion. The NADPH oxidase consists of 6 subunits, including the membrane-bound p91 phox and p22 phox heterodimers (also known as cytochrome b558), the cytosolic complex of p40phox, p47phox and p67phox, and the small GTPase Rac2. Activation of NADPH oxidase is initiated by cytosolic complex phosphorylation, which induces a conformational change that leads to the translocation of the cytosolic complex to the membrane and formation of an active enzyme with cytochrome b558 (1). Defects in p47phox, often resulting from recombination betwe |
Immunogen | Immunogen: Recombinant protein of human NCF1 |
Other Names | [neutrophil cytosol factor 1; Neutrophil cytosol factor 1; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox], [NCF1; NCF1; NCF1A; NOXO2; p47phox; SH3PXD1A; NOXO2; SH3PXD1A; NCF-1] |
Gene, Accession # | [NCF1], Gene ID: 653361, NCBI: NP_000256.4 |
Catalog # | MBS419561 |
Price | $385 |
Order / More Info | NCF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |