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Antigenic Specificity | Checkpoint protein HUS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Checkpoint protein HUS1 polyclonal antibody. Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex.Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA lig |
Immunogen | Immunogen: Recombinant Human Checkpoint protein HUS1 protein |
Other Names | [HUS1] |
Gene, Accession # | Gene ID: 3364, NCBI: NP_004498.1, UniProt: O60921 |
Catalog # | MBS9416184 |
Price | $320 |
Order / More Info | Checkpoint protein HUS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |