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Antigenic Specificity | DNMT3L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), ELISA (EIA), Chromatin Immunoprecipitation (ChIP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DNMT3L antibody detects endogenous levels of total DNMT3L. Description: Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and development (1, 2). Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3 (1, 2). DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues. DNMT3A and DNMT3B function as de novo methyltransf |
Immunogen | Immunogen: A synthesized peptide derived from human DNMT3L Subcellular Location: Nucleus. Tissue Specificity: Expressed at low levels in several tissues including testis, ovary, and thymus. Predicted Cross Reactivity: Pig, Dog Similarity: Pig (90%), Dog (89%) |
Other Names | [Cytosine 5 methyltransferase 3 like protein; DNA (cytosine 5) methyltransferase 3 like; DNA (cytosine-5)-methyltransferase 3-like; DNA cytosine 5 methyltransferase 3 like protein; DNA methyltransferase 3 like protein; DNM3L_HUMAN; Dnmt 3L; Dnmt3l; Human cytosine 5 methyltransferase 3 like protein; MGC1090] |
Gene, Accession # | [DNMT3L], Gene ID: 29947, NCBI: NP_037501.2, UniProt: Q9UJW3 |
Catalog # | MBS9607581 |
Price | $240, $280 |
Order / More Info | DNMT3L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |