Vimentin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVimentin
Clone[RV203]
Host SpeciesMouse
Reactive Speciesdog, Caprine, hamster, human, rat, porcine
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC), Immunocytochemistry (IHC), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB)
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DescriptionSpecificity: RV203 reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors e.g. lymphoma, sarcoma and melanoma. Vimentin (57 kDa) is the intermediate filament protein (IFP) of mesenchymal cells. This IFP however often deviates from the tissue-specific and developmentally regulated pattern of expression. Besides its typical expression in most cultured cells, vimentin is also expressed together with several other IFPs during early stages of development. As differentiation proceeds, vimentin is exchanged for the tissue-specific intermediate filament type. Also in cancers, vimentin is often expressed in addition to the tissue-specific IFP.
ImmunogenSource Note: RV203 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with a cytoskeletal vimentin extract of calf lens.
Other Names[vimentin; Vimentin; vimentin; OTTHUMP00000019224; OTTHUMP00000019225; vimentin], [VIM; VIM; FLJ36605]
Gene, Accession #Gene ID: 7431, NCBI: NP_003371.2, UniProt: P08670
Catalog #MBS570009
Price$510
Order / More InfoVimentin Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchaart, G., Pieper, F. R., Kuijpers, H. J., Bloemendal, H., and Ramaekers, F. C. (1991). Baby Hamster kidney (BHK-21/C13) cells can express striated muscle type proteins, Differentiation 46, 105-15.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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