Edit |   |
---|---|
Antigenic Specificity | ILPIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-ILPIP is specific for human ILPIP only. ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1b converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter is |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP. |
Other Names | [STE20-related kinase adapter protein beta isoform 1; STE20-related kinase adapter protein beta; STE20-related kinase adapter protein beta; STE20-related kinase adaptor beta; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS-21; ILP-interacting protein; Pseudokinase ALS2CR2] |
Gene, Accession # | [ILPIP], Gene ID: 55437, NCBI: NP_061041 |
Catalog # | MBS9408397 |
Price | $320 |
Order / More Info | ILPIP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |