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Antigenic Specificity | Cleaved-Caspase-5 p10 (S331) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p10 protein resulting from cleavage adjacent to S331. CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of caspase 5 induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and a |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370 |
Other Names | [Rabbit Cleaved-Caspase-5 p10 (S331); ICH3; Caspase-5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY] |
Gene, Accession # | [CASP5], Gene ID: 838, NCBI: NP_001129581.1, UniProt: P51878 |
Catalog # | MBS9700797 |
Price | $130, $220, $325 |
Order / More Info | Cleaved-Caspase-5 p10 (S331) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |