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Antigenic Specificity | KLB (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This KLB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from human KLB. Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity). |
Immunogen | n/a |
Other Names | [Beta-klotho; BKL; BetaKlotho; Klotho beta-like protein; KLB] |
Gene, Accession # | [KLB], Gene ID: 152831, NCBI: NP_783864.1, UniProt: Q86Z14 |
Catalog # | MBS9217205 |
Price | $165, $370 |
Order / More Info | KLB (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hayashi A.,et al.Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases. Wu X.,et al.J. Biol. Chem. 283:33304-33309 (2008). Micanovic R.,et al.J. Cell. Physiol. 219:227-234 (2009). |