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Antigenic Specificity | Human/Mouse CD11a |
Clone | [TS1/22.1.1.13] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1alpha chain and integrin alphaL subunit. CD11a non-covalently associates with integrin beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
Immunogen | n/a |
Other Names | [Human CD11a; Integrin alpha-L; Itgal; CD11 antigen-like family member A; LFA-1A; Lymphocyte antigen 15; Ly-15; CD11a] |
Gene, Accession # | [CD11a], Gene ID: 368316408, NCBI: NP_001107852.1, UniProt: P20701 |
Catalog # | MBS2553835 |
Price | $70, $105 |
Order / More Info | Human/Mouse CD11a Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lub M, et al. 1995. Immunol. Today 16:479. 2. Parsons J. 1996. Curr. Opin. Cell Biol. 8:146. |