DKK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDKK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of Dkk1 and Dkk2 inhibited Wnt-3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of Dkk-2, but not that of Dkk-1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 255 of mouse Dkk1
Other Names[DKK-1; DKK1; SK; dickkopf homolog 1; dickkopf-1; dickkopf-1 like], [Dkk1; Dkk1; mdkk-1; Dickkopf-1; Dkk-1; mDkk-1]
Gene, Accession #[DKK1], Gene ID: 13380, NCBI: NP_034181.2, UniProt: O54908
Catalog #MBS841192
Price$150, $300
Order / More InfoDKK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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