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Antigenic Specificity | Human FAP ALPHA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects fibroblast activation protein alpha (FAP alpha), a type II membrane protein belonging to the serine protease family. FAP alpha is upregulated on activated fibroblasts in response to wounding, and may also be involved in epithelial-mesenchymal interactions during development and tissue repair.. . Active FAP alpha is a 170kD homodimeric protein which can also exist as a soluble form. FAP alpha can also form heterodimeric complexes with CD26 (DPP4), and these proteins may function co-ordinately to modulate the growth, differentiation, adhesion and metastasis of tumour cells. MBS222803 detects fibroblast activation protein alpha (FAP alpha), a type II membrane protein belonging to the serine protease family. FAP alpha is upr |
Immunogen | Immunogen: Synthetic peptide: extracellular domain of human FAP alpha, conjugated to keyhole limpet hemocyanin. Histology Positive Control Tissue: Uterus Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to FAP alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [prolyl endopeptidase FAP isoform 2; Prolyl endopeptidase FAP; prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; FAPalpha; dipeptidyl peptidase FAP; gelatine degradation protease FAP; integral membrane serine protease; post-proline cleaving enzyme; seprase; serine integral membrane protease; surface-expressed protease; fibroblast activation protein, alpha; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; Fibroblast activation protein alpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Surface-expressed protease;], [FAP; FAP; FAPA; SIMP; DPPIV] |
Gene, Accession # | Gene ID: 2191, NCBI: NP_001278736.1, UniProt: Q12884 |
Catalog # | MBS222803 |
Price | $550 |
Order / More Info | Human FAP ALPHA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |