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Antigenic Specificity | Phospho-RB1-S795 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S795 of human RB1 Calculated Molecular Weight: 110kDa |
Other Names | [Phospho-RB1-S795: RB; pRb; OSRC; pp110; p105-Rb], [RB1; RB1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; Rb] |
Gene, Accession # | [RB1], Gene ID: 5925, NCBI: P06400.2, UniProt: P06400 |
Catalog # | MBS128255 |
Price | $235, $350, $525 |
Order / More Info | Phospho-RB1-S795 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |