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Antigenic Specificity | Human BACE1 (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises human beta-site APP-cleaving enzyme 1 (BACE1), a 70kD aspartic protease. BACE1 is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease. MBS222470 recognises human beta-site APP-cleaving enzyme 1 (BACE1), a 70kD aspartic protease. BACE1 is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease. |
Immunogen | Immunogen: Synthetic peptide CLRQQHDDFADDISLLK corresponding to the C-terminal amino sequence 458-501 of human BACE. Antiserum Preparation: Antisera to human BACE1 (C-terminal) were raised by repeated immunisations of goats with highly purified antigen. Target Species: Human |
Other Names | [beta-secretase 1 isoform F; Beta-secretase 1; beta-secretase 1; APP beta-secretase; asp 2; aspartyl protease 2; beta-secretase 1 precursor variant 1; beta-site APP cleaving enzyme 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; memapsin-2; membrane-associated aspartic protease 2; transmembrane aspartic proteinase Asp2; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2], [BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2; Beta-site APP cleaving enzyme 1] |
Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817 |
Catalog # | MBS222470 |
Price | $375 |
Order / More Info | Human BACE1 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |