Edit |   |
---|---|
Antigenic Specificity | ASK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ASK1 is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent fashion in response to an array of stresses such as oxidative stress, endoplasmic reticulum stress and calcium influx. ASK1 has been found to be involved in cancer, diabetes, cardiovascular and neurodegenerative diseases. |
Immunogen | Immunogen: ASK1 antibody was raised in Rabbit using the peptide sequence around aa 964~968 (S-I-S-L-P) derived from Human ASK1 as the immunogen. |
Other Names | [Rabbit ASK1; ASK1; ASK1; ASK 1; ASK-1; ASK 1; ASK-1; Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK1; Ab 966; MAP3K5] |
Gene, Accession # | [ASK1], NCBI: CEP23956.1 |
Catalog # | MBS5309722 |
Price | $295 |
Order / More Info | ASK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |