S100A8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | S100A8 |
| Clone | [IMG48M7C7] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect S100A8 in human and mouse samples. Background: S100A8 is a low-molecular weight member of the S100 family of calcium-binding protein which promotes tumorigenesis. It promotes cell migration and invasion through p38 MAP dependent NF-kappaB activation leading to an increase of MMP2 and MMP12 in gastric cancer. The phagocyte-specific Ca2+-binding S100A8 protein has been proposed as an essential regulator of the plasma membrane NADPH oxidase activity. It is abundantly expressed in the cytosol of neutrophils and is able to form Ca2+-dependent heterocomplexes, with heterotetramers being a probable prerequisite for its biological activities in myeloid cells. S100A8 and S100A9 have been proposed as essential regulators |
| Immunogen | Immunogen: Amino acids 2-93 of human S100A8. Positive Control: Western blot: human spleen, HL60 and PC3 lysate, IHC: paraffin-embedded human spleen |
| Other Names | [Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; S100 calcium-binding protein A8; Urinary stone protein band A], [S100A8; S100A8; P8; MIF; NIF; CAGA; CFAG; CGLA; L1Ag; MRP8; CP-10; MA387; 60B8AG; CAGA; CFAG; MRP8; CFAG; MRP-8; p8] |
| Gene, Accession # | [S100A8], Gene ID: 6279, NCBI: NP_002955.2, UniProt: P05109 |
| Catalog # | MBS840011 |
| Price | $450 |
| Order / More Info | S100A8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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