DNA-(apurinic or apyrimidinic site) lyase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DNA-(apurinic or apyrimidinic site) lyase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | caprylic acid ammonium sulfate precipitate |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total DNA-(apurinic or apyrimidinic site) lyase polyclonal antibody. Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RN |
| Immunogen | Immunogen: Recombinant Human DNA-(apurinic or apyrimidinic site) lyase Protein |
| Other Names | [APEX nuclease; Apurinic-apyrimidinic endonuclease 1; REF-1; Redox factor-1; APEX1; APE; APE1; APEX; APX; HAP1; REF1] |
| Gene, Accession # | Gene ID: 328, NCBI: NP_001231178.1, UniProt: P27695 |
| Catalog # | MBS9415882 |
| Price | $320 |
| Order / More Info | DNA-(apurinic or apyrimidinic site) lyase Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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