Mouse PD-L1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse PD-L1 |
| Clone | [10F.9G2] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation |
| Immunogen | n/a |
| Other Names | [B7-H1; PD-L1; Programmed cell death ligand 1; B7 homolog 1; B7-H; B7H1; PDL1; PDCD1L1; PDCD1LG1] |
| Gene, Accession # | [PD-L1], Gene ID: 60533, NCBI: NP_068693.1, UniProt: Q9EP73 |
| Catalog # | MBS2556975 |
| Price | $75, $90 |
| Order / More Info | Mouse PD-L1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sharpe A, et al. 2007. Nat. Immunol. 8:239. 2. Dong H, et al. 1999. Nat. Med. 5:1365. 3. Freeman G, et al. 2000. J. Exp. Med. 192:1027. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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