IL12RB1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IL12RB1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Interleukin-12 receptor subunit beta-1 (IL12RB1) detection. Background: IL12RB1, mapped to 19p13.11, is also known as CD212. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. And this protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphoc |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IL12RB1 (624-662aa DKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKAKM). |
| Other Names | [CD212; IL-12R-beta-1; IL-12RB1; IL12RB; Il12rb1; IMD3; IMD30; P42701; Interleukin-12 receptor subunit beta-1], [IL12RB1; IL12RB1; CD212; IMD30; IL12RB; IL-12R-BETA1; IL12R; IL12RB; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1] |
| Gene, Accession # | [IL12RB1], Gene ID: 3594, NCBI: NP_001276952.1, UniProt: P42701 |
| Catalog # | MBS178682 |
| Price | $280 |
| Order / More Info | IL12RB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: IL12RB1 interleukin 12 receptor, beta 1.2. Altare F, Ensser A, Breiman A, et al. (2001). Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis. J. Infect. Dis. 184 (2): 231-6.3. Parham C, Chirica M, Timans J, et al. (2002). A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J. Immunol. 168 (11): 5699-708. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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