CD4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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DescriptionCluster of Differentiation 4 (CD4) is a glycoprotein composed of an aminoterminal extracellular domain (four domains: D1-D4 with Ig-like structures), a transmembrane part and a short cytoplasmic tail. CD4 is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells, and plays an important role in the development and activation of T cells. On T cells, CD4 is the co-receptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen-Major Histocompatibility Complex (MHC). Specifically, the D1 domain of CD4 interacts with the beta2-domain of the MHC class II molecule. CD4 ensures specificity of the TCR-antigen interaction, prolongs the contact between the T cell and t
ImmunogenImmunogen: A synthetic -peptide of human CD4
Other Names[CD4; CD4; CD4; CD4; CD4mut; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3;], [CD4; CD4; CD4mut]
Gene, Accession #Gene ID: 920, NCBI: NP_000607.1, UniProt: P01730
Catalog #MBS125302
Price$200, $275, $430
Order / More InfoCD4 Antibody from MYBIOSOURCE INC.
Product Specific References1. Zamoyska, R. (1994) Immunity 1, 243-246.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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