HSP27 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HSP27 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | HSP27 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, shark, dog |
| Isotype | n/a |
| Format | APC-Cy7 conjugate |
| Size | 0.2 mg |
| Concentration | 1.38 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~27 kDa. HSP27s belong to an abundant and ubiquitous family of small heat shock proteins (sHSP). It is an important HSP found in both normal human cells and cancer cells. The basic structure of most sHSPs is a homologous and highly conserved amino acid sequence, with an alpha-crystallin domain at the C-terminus and the WD/EPF domain at the less conserved N-terminus. This N-terminus is essential for the development of high molecular oligomers (1, 2). HSP27-oligomers consist of stable dimers formed by as many as 8-40 HSP27 protein monomers (3). The oligomerization status is connected with the chaperone activity: aggregates of large oligomers have high chaperone activity, whereas dimers have no chaperone activity (4). HSP27 is localize |
| Immunogen | Immunogen: Human HSP27, His tagged |
| Other Names | [Rabbit Human HSP27; 28kDa heat shock protein; CMT2F; HSP25; HSP27; HSP28; HSPB1; SRP27] |
| Gene, Accession # | [HSP27], Gene ID: 3315, NCBI: NP_001531.1, UniProt: P04792 |
| Catalog # | MBS8004073 |
| Price | $585 |
| Order / More Info | HSP27 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kim K.K., Kim R., and Kim, S. (1998) Nature 394(6693): 595-599. 2. Van Montfort R., Slingsby C., and Vierling E. (2001) Addv Protein Chem. 59: 105-56. 3. Ehrnsperger M., Graber S., Gaestel M. and Buchner J. (1997) EMBO J. 16: 221-229. 4. Ciocca D.R., Oesterreich S., Chamness G.C., McGuire W.L., and Fugua S.A. (1993) J Natl Cancer Inst. 85 (19): 1558-70. 5. Sarto C., Binnz P.A., and Mocarelli P. (2000) Electrophoresis. 21(6): 1218-26. 6. Arrigo A.P. (2005) J Cell Biochem. 94(2): 241-6. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies