TRAF1 (TNFR-Associated Factor 1) (Lymphomatoid Papulosis Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAF1 (TNFR-Associated Factor 1) (Lymphomatoid Papulosis Marker)
Clone[TRAF1/2770]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistology (Formalin-Fixed)
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DescriptionThis MAb recognizes a protein of 52kDa, which is identified as TNFR1 (TNFR-associated factor 1). CD30-positive lymphoproliferations of the skin comprise 30% of all primary cutaneous T-cell lymphomas (CTCLs). Besides borderline cases this group includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large T-cell lymphoma (cALCL). Although the two entities overlap clinically, histopathologically, immunopathologically and genetically, they differ considerably in their prognosis. In particular, common feature of both cases is histologically the presence of atypical lymphoid CD30-positive T blasts and genetically a clonal T-cell-receptor rearrangement. However, both cases differ considerably in their clinical course: Lesions of Ly
ImmunogenImmunogen: Recombinant fragment of human TRAF1 protein (around aa 73-219) (exact sequence is proprietary) Positive Control: HeLa or 293T Cells. Hodgkins Lymphoma
Other Names[EBI6; EBV induced protein 6; Epstein-Barr virus-induced protein 6; TNF receptor-associated factor 1; TRAF1]
Gene, Accession #[TRAF1], Gene ID: 7185, NCBI: NP_001177874.1, UniProt: Q13077
Catalog #MBS4380706
Price$190, $340, $340
Order / More InfoTRAF1 (TNFR-Associated Factor 1) (Lymphomatoid Papulosis Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAssaf C., et al. J Invest Dermatol 127(8):1898-1904, 2007
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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