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Antigenic Specificity | DDIT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts from mouse craniofacial tissue, using DDIT3 antibody. Immunohistochemistry of paraffin-embedded mouse spleen using DDIT3 antibody at dilution of 1:100 (400x lens). Immunohistochemistry of paraffin-embedded rat kidney using DDIT3 antibody at dilution of 1:100 (200x lens). DDIT3 was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner (1). DDIT3 expression is induced by certain cellular stresses including starvation and the induced DDIT3 suppresses cell cycle progression from G1 to S phase (2). Later it was shown that, during ER stress, the level of DDIT3 expression is elevated and DDIT3 functions to mediate programmed cell death (3). Studies also fou |
Immunogen | Immunogen: Recombinant protein of human DDIT3 |
Other Names | [DNA damage-inducible transcript 3 protein isoform 2; DNA damage-inducible transcript 3 protein; DNA damage-inducible transcript 3 protein; DNA damage inducible transcript 3; C/EBP zeta; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; CCAAT/enhancer-binding protein homologous protein; Growth arrest and DNA damage-inducible protein GADD153], [DDIT3; DDIT3; CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; CHOP; CHOP10; GADD153; DDIT-3; CHOP; CHOP-10] |
Gene, Accession # | [DDIT3], Gene ID: 1649, NCBI: NP_001181986.1, UniProt: P35638 |
Catalog # | MBS419387 |
Price | $385 |
Order / More Info | DDIT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |