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Antigenic Specificity | BCL10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of ovary cell and lung cell lysate using BCL10 antibody. Immunohistochemistry of paraffin-embedded human breast cancer using BCL10 antibody at dilution of 1:500 (400x lens). Immunofluorescence analysis of A549 cell using BCL10 antibody. Blue: DAPI for nuclear staining. Bcl10/CIPER/CLAP/mE10 is a widely expressed CARD (caspase recruitment domain) containing protein shown to induce apoptosis and activate NF-B (1-5). The CARD domain mediates self-oligomerization, interactions with other CARD proteins and is necessary for NF-B activation, although the precise mechanism which Bcl10 regulates these processes is not fully understood. The discovery of Bcl10 came from observations of the chromosomal translocation t |
Immunogen | Immunogen: Recombinant protein of human BCL10 |
Other Names | [B-cell lymphoma/leukemia 10 isoform 2; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10], [BCL10; BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10] |
Gene, Accession # | [BCL10], Gene ID: 8915, NCBI: NP_001307644.1 |
Catalog # | MBS419540 |
Price | $385 |
Order / More Info | BCL10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |