IL12RB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL12RB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
ImmunogenImmunogen: Recombinant protein of human IL12RB1 Immunogen Species: Human
Other Names[CD212; IL-12R-BETA1; IL12RB; IMD30]
Gene, Accession #[IL12RB1], Gene ID: 3594, NCBI: NP_001276952.1, UniProt: P42701
Catalog #MBS9133363
Price$200, $275, $430
Order / More InfoIL12RB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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