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Antigenic Specificity | Mouse CD137 |
Clone | [17B5] |
Host Species | Hamster |
Reactive Species | n/a |
Isotype | IgG |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hamster anti Mouse CD137 antibody, clone 17B5 recognizes mouse CD137, also known as 4-1BB ligand receptor, a member of the tumour necrosis factor superfamily. CD137 is a potent costimulatory receptor for the growth and functional maturation of activated T-cells in the presence of T-cell receptor signal. It is found on activated T-cells, NK cells, monocytes and dendritic cells. Signalling through CD137 triggers T-cell expansion, cytokine production and prevention of activation-induced death of effector T-cells. CD137-mediated activation is distinct from and independent of CD28. Antibody cross-linking of CD137 on NK cells stimulates the secretion of IFN-gamma, cellular proliferation, CD25 expression and responsiveness to IL-2 and is associate |
Immunogen | n/a |
Other Names | [tumor necrosis factor receptor superfamily member 9 isoform 1; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CD137 antigen; T-cell antigen 4-1BB; secreted CD137 antigen; tumor necrosis factor receptor superfamily, member 9; 4-1BB ligand receptor; T-cell antigen 4-1BB; CD_antigen: CD137], [Tnfrsf9; Tnfrsf9; ILA; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik; Cd137; Ila; Ly63] |
Gene, Accession # | [CD137], Gene ID: 21942, NCBI: NP_001070977.1, UniProt: P20334 |
Catalog # | MBS219625 |
Price | $430 |
Order / More Info | Mouse CD137 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |