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Antigenic Specificity | c-CBL |
Clone | [3B12] |
Host Species | Mouse |
Reactive Species | mouse, rat, human |
Isotype | IgG1 |
Format | ascites |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CBL. CBL Antibody, C-CBL Antibody, Oncogene CBL2 Antibody, RING finger protein 55 Antibody, Proto-oncogene c-Cbl Antibody, RNF55 Antibody, CBL2 Antibody, FRA11B Antibody, NSLL Antibody Description: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling. |
Immunogen | Immunogen Description: Purified recombinant fragment of human C-CBL expressed in E Coli. Immunogen Type: Recombinant protein |
Other Names | [Mouse [clone 3B12] (IgG1) to Human c-CBL; Human c-CBL; C-CBL; Oncogene CBL2; RING finger protein 55; Proto-oncogene c-Cbl; RNF55; CBL2; FRA11B; NSLL], [CBL; CBL; CBL2; NSLL; C-CBL; RNF55; FRA11B; CBL2; RNF55] |
Gene, Accession # | [CBL], Gene ID: 867, NCBI: NP_005179.2, UniProt: P22681 |
Catalog # | MBS249486 |
Price | $530 |
Order / More Info | c-CBL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |