c-CBL Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-CBL
Clone[3B12]
Host SpeciesMouse
Reactive Speciesmouse, rat, human
IsotypeIgG1
Formatascites
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionSpecificity: Human CBL. CBL Antibody, C-CBL Antibody, Oncogene CBL2 Antibody, RING finger protein 55 Antibody, Proto-oncogene c-Cbl Antibody, RNF55 Antibody, CBL2 Antibody, FRA11B Antibody, NSLL Antibody Description: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling.
ImmunogenImmunogen Description: Purified recombinant fragment of human C-CBL expressed in E Coli. Immunogen Type: Recombinant protein
Other Names[Mouse [clone 3B12] (IgG1) to Human c-CBL; Human c-CBL; C-CBL; Oncogene CBL2; RING finger protein 55; Proto-oncogene c-Cbl; RNF55; CBL2; FRA11B; NSLL], [CBL; CBL; CBL2; NSLL; C-CBL; RNF55; FRA11B; CBL2; RNF55]
Gene, Accession #[CBL], Gene ID: 867, NCBI: NP_005179.2, UniProt: P22681
Catalog #MBS249486
Price$530
Order / More Infoc-CBL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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