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Antigenic Specificity | Human UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Involved in insulin resistance in muscle and adipocyte cells via glycosylating insulin signaling components and inhibiting the Thr-308 phosphorylation of AKT1, enhancing IRS1 phosphorylation and attenuating insulin signaling. Involved in glycolysis regulation by medi |
Immunogen | Immunogen: Recombinant human UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit protein(606-1022aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22625 / sc-22628 / sc-32921 |
Other Names | [O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT], [OGT; OGT; HRNT1; HINCUT-1; O-GLCNAC; OGT] |
Gene, Accession # | Gene ID: 8473, NCBI: NP_858058.1, UniProt: O15294 |
Catalog # | MBS1492824 |
Price | $160, $235 |
Order / More Info | Human UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |