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Antigenic Specificity | JNKK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total JNKK protein. Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human JNKK. |
Other Names | [C-JUN N-terminal kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 4; EC 2.7.12.2; JNK activating kinase 1; JNK kinase 1] |
Gene, Accession # | [JNKK], Gene ID: 6416, NCBI: NP_001268364.1, UniProt: P45985 |
Catalog # | MBS9410232 |
Price | $200, $255 |
Order / More Info | JNKK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |