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Antigenic Specificity | EPHA5 |
Clone | [46CT61.6.4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1κ |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged EPHA5 protein(Fragment) was used to produced this monoclonal antibody. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | [Ephrin type-A receptor 5; Brain-specific kinase; EPH homology kinase 1; EHK-1; EPH-like kinase 7; EK7; hEK7; EPHA5; BSK; EHK1; HEK7; TYRO4] |
Gene, Accession # | [EPHA5], Gene ID: 2044, NCBI: NP_004430.4, UniProt: P54756 |
Catalog # | MBS9200568 |
Price | $165, $370 |
Order / More Info | EPHA5 Antibody from MYBIOSOURCE INC. |
Product Specific References | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma. Giaginis C, et al. Pathol Oncol Res, 2010 Jun. PMID 19949912. Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. Fu DY, et al. Hum Pathol, 2010 Jan. PMID 19733895. Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival. Herath NI, et al. BMC Cancer, 2006 Jun 1. PMID 16737551. The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901. |