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Antigenic Specificity | GADD45B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.5 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total GADD45B protein. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Full length fusion protein |
Other Names | [MYD118; GADD45BETA] |
Gene, Accession # | [GADD45B], Gene ID: 4616, NCBI: NP_056490.2, UniProt: O75293 |
Catalog # | MBS9404665 |
Price | $255 |
Order / More Info | GADD45B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |