Edit |   |
---|---|
Antigenic Specificity | XRCC1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: XRCC1(X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 1) is a DNA repair protein which complexes with DNA ligase III. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. The XRCC1 gene is mapped to 19q13.31. The XRCC1 interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and Recombinantion in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. XRCC1 is phosphorylated in vivo and in vitro by CK2, and CK2 p |
Immunogen | Immunogen: E Coli-derived human XRCC1 recombinant protein (Position: E538-A633). Subcellular Localization: Nucleus. |
Other Names | [DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; XRCC1] |
Gene, Accession # | [XRCC1], Gene ID: 7515, NCBI: NP_006288.2, UniProt: P18887 |
Catalog # | MBS1750437 |
Price | $315 |
Order / More Info | XRCC1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |