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Antigenic Specificity | hnRNP A1 (Ab-192) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total hnRNP A1 protein. Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts. hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells. Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus. hnRNP A |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.190~194(S-S-S-Q-R)derived from Human hnRNP A1. |
Other Names | [HNRPA1; HNRPA1L3; hnRNP A1; hnRNP-A1; MGC102835] |
Gene, Accession # | [hnRNP A1], Gene ID: 3178, NCBI: NP_002127.1, UniProt: P09651 |
Catalog # | MBS9407324 |
Price | $200, $255 |
Order / More Info | hnRNP A1 (Ab-192) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |