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Antigenic Specificity | LAMP1 |
Clone | [Ly1C6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, hamster |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.025 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~120kDa. Lysosme associated membrane proteins, or LAMP1 and LAMP2, are major constituents of the lysosomal membrane. The two have closely related structures, with 37% sequence homology (2). They are both transmembrane glycoproteins that are localized primarily in lysosomes and late endosomes. Newly synthesized molecules are mostly transported from the trans-Golgi network directly to endosomes and then to lysosomes. A second pathway involves the lamps being delivered from the Golgi to the cell surface, and then along the endocytic pathway to the lysosomes. A minor pathway involves transport via the plasma membrane (3). Upon stimulation, a rapid translocation of intracellular LAMPs to the cell membrane is dependent on a carboxyl~termi |
Immunogen | Immunogen: Rat liver lysosomal membrane preparations Immunogen Species: Rat |
Other Names | [Mouse Rat LAMP1 IgG1; LAMP1, Clone Ly1C6; CD107; CD107a; LAMPA; LGP120; IgpA; Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; 120 kDa lysosomal membrane glycoprotein; Lamp-1] |
Gene, Accession # | [LAMP1], Gene ID: 25328, NCBI: P14562.1, UniProt: P14562 |
Catalog # | MBS8001892 |
Price | $255 |
Order / More Info | LAMP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Grutzkau, A. et al (2004) Cytometry A. 61(10): 62-68. 2. Furuta, K. et al. (1999) EMBO J. 17(5):1304-14. 3. Rohrer, J. et al. (1996) J Cell Biol. 132(4): 565-76. 4. Kannan, K., et al. (1996) Cell Immunol. 171: 10-19. 5. Lewis, V., et al. (1985) J. Cell Biol. 100: 1839-1847. 6. Jones, K.A., et al. (2004) Exp Cell Res 295(2): 512-524. |