DDX58 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDDX58
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionAntiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and antiviral enzymes (1-3). TLRs and helicase proteins contain sites that recognize the molecular patterns of different virus types, including DNA, single-stranded RNA (ssRNA), double-stranded RNA (dsRNA), and glycoproteins. These antiviral proteins are found in different cell compartments; TLRs (i.e. TLR3, TLR7, TLR8, and TLR9) are expressed on endosomal membranes and helicases are localized to the cytoplasm.
ImmunogenImmunogen: A synthetic peptide of human DDX58 Calculated Molecular Weight: 107kDa
Other Names[Rig-I: DDX58; DKFZp434J1111; DKFZp686N19181; FLJ13599; RIG-I], [DDX58; DDX58; RIGI; RIG-I; RLR-1; RLR-1; RIG-1; RIG-I]
Gene, Accession #[DDX58], Gene ID: 23586, NCBI: O95786.2, UniProt: O95786
Catalog #MBS125909
Price$200, $275, $430
Order / More InfoDDX58 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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