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Antigenic Specificity | YWHAE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total YWHAE protein. The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways (1,2). 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, b, g, eta, sigma, zeta, tau, and eta that have been identified in mammals. The initially described a and d isoforms are confirmed to be phosphorylated forms of b and zeta, respectively (3). Through their amino-terminal a helical region, 14-3-3 proteins form homo- or heterodimers that interact with a wide variety of proteins: transcription factors, metabolic enzymes, cytoskeletal proteins, kinases, phosphatases, and other signaling mole |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human YWHAE. |
Other Names | [YWHAE; 14-3-3E; FLJ45465; KCIP-1; MDCR] |
Gene, Accession # | [YWHAE], Gene ID: 7531, NCBI: NP_006752.1, UniProt: P62258 |
Catalog # | MBS9402282 |
Price | $255 |
Order / More Info | YWHAE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |