Phospho-HS1(Tyr378) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-HS1(Tyr378) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-HS1(Tyr378) antibody detects endogenous levels of HS1 only when phosphorylated at Tyrosine 378. Function: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.Subunit Structure: Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly asso |
| Immunogen | Immunogen: A synthesized peptide derived from human HS1 around the phosphorylation site of Tyrosine 378 Subcellular Location: Membrane. Cytoplasm. Mitochondrion. Tissue Specificity: Expressed only in tissues and cells of hematopoietic origin. |
| Other Names | [Cortactin like; CTTNL; HCLS 1; Hcls1; HCLS1_HUMAN; Hematopoietic cell specific Lyn substrate 1; Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; HS 1; HS1; LckBP1; OTTHUMP00000215180; OTTHUMP00000215182; p75] |
| Gene, Accession # | [HS1], Gene ID: 3059, NCBI: NP_001278970.1, UniProt: P14317 |
| Catalog # | MBS9600030 |
| Price | $240, $280 |
| Order / More Info | Phospho-HS1(Tyr378) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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