IL33 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL33 |
| Clone | [4E9] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. |
| Immunogen | Immunogen: Recombinant human IL-33 (112-270aa) purified from E. coli |
| Other Names | [Interleukin 33; DVS27; NF-HEV; NKHEV; C9orf26; IL-33; Interleukin 33 CHROMOSOME 9 OPEN READING FRAME 26; DKFZp586H0523; DVS27 related protein; IL 1F11; IL 33; IL1F11; Interleukin 1 family member 11; INTERLEuKIN 33 NFHEV; Interleukin 33 precursor; Interleukin33; NF HEV; NFHEV; Nuclear factor from high endothelial venules; RP11 575C20.2; il33], [IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV] |
| Gene, Accession # | [IL33], Gene ID: 90865, NCBI: NP_254274, UniProt: O95760 |
| Catalog # | MBS200087 |
| Price | $240, $315 |
| Order / More Info | IL33 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Brint Ek, et al., (2005) J Biol Chem. 20:277 (51); Schmitz, et al., (2005) immunity. 23:479; Baekkevold ES, et al., (2003) Am.J.Pathol. 163 (1):69-90 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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