PCGF6 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPCGF6 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsImmunofluorescence (IF), ELISA (EIA), Western Blot (WB)
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DescriptionThis PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human PCGF6. Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Immunogenn/a
Other Names[Polycomb group RING finger protein 6; Mel18 and Bmi1-like RING finger; RING finger protein 134; PCGF6; MBLR; RNF134]
Gene, Accession #[PCGF6], Gene ID: 84108, NCBI: NP_001011663.1, UniProt: Q9BYE7
Catalog #MBS9203828
Price$165, $370
Order / More InfoPCGF6 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAkasaka T.,et al.Genes Cells 7:835-850(2002). Ota T.,et al.Nat. Genet. 36:40-45(2004). Deloukas P.,et al.Nature 429:375-381(2004). Lee M.G.,et al.Cell 128:877-887(2007). Maertens G.N.,et al.PLoS ONE 4:E6380-E6380(2009).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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