Mouse Epha2 (Center), 296-323 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Epha2 (Center), 296-323 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Epha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of mouse Epha2. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell inter |
| Immunogen | n/a |
| Other Names | [Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; Tyrosine-protein kinase receptor SEK-2; Epha2; Eck; Myk2; Sek2] |
| Gene, Accession # | [Epha2], Gene ID: 13836, NCBI: NP_034269.2, UniProt: Q03145 |
| Catalog # | MBS9210506 |
| Price | $165, $370 |
| Order / More Info | Mouse Epha2 (Center), 296-323 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010) Kim, J., et al. Mol. Cell. Biol. 30(7):1582-1592(2010) Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009) Jun, G., et al. PLoS Genet. 5 (7), E1000584 (2009) : North, H.A., et al. Development 136(14):2467-2476(2009) |
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