SETX Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SETX |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription (PubMed:19515850, PubMed:21700224). Contributes to the mRNA splicing efficiency and splice site selection (PubMed:19515850). Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (PubMed:19515850, PubMed:21700224). Required for the 3' trans |
| Immunogen | Immunogen: Recombinant human Probable helicase senataxin protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135405 |
| Other Names | [Probable helicase senataxinCurated (EC:3.6.4.-); SETX1; Amyotrophic lateral sclerosis 4 protein; SEN1 homologCurated; Senataxin1], [SETX; SETX; ALS4; AOA2; SCAR1; bA479K20.2] |
| Gene, Accession # | [SETX], Gene ID: 23064, NCBI: NP_055861.3, UniProt: Q7Z333 |
| Catalog # | MBS1494067 |
| Price | $160, $235 |
| Order / More Info | SETX Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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