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Antigenic Specificity | CD32 (Phospho-Tyr292) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989).Brooks D.G., J. Exp. Med. 170:1369-1385(1989).Engelhardt W., Eur. J. Immunol. 20:1367-137 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32. |
Other Names | [CD32; FCG2; FCG2B,; LY-17; CDW32] |
Gene, Accession # | [CD32], Gene ID: 2213, NCBI: NP_001002273.1, UniProt: P31994 |
Catalog # | MBS9412345 |
Price | $200, $255 |
Order / More Info | CD32 (Phospho-Tyr292) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |