CD32 (Phospho-Tyr292) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD32 (Phospho-Tyr292)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989).Brooks D.G., J. Exp. Med. 170:1369-1385(1989).Engelhardt W., Eur. J. Immunol. 20:1367-137
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.
Other Names[CD32; FCG2; FCG2B,; LY-17; CDW32]
Gene, Accession #[CD32], Gene ID: 2213, NCBI: NP_001002273.1, UniProt: P31994
Catalog #MBS9412345
Price$200, $255
Order / More InfoCD32 (Phospho-Tyr292) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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