Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker)
Clone[SPM361]
Host SpeciesMouse
Reactive Specieshuman and rat.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistology (Formalin-fixed)
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DescriptionRecognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm's tumors. WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, mali
ImmunogenImmunogen: Recombinant protein corresponding to residues 1-181 of human WT1. Cellular Localization: Nuclear and Cytoplasmic. Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.
Other Names[WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1], [WT1; WT1; GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1]
Gene, Accession #[WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544
Catalog #MBS439403
Price$190, $340, $340
Order / More InfoWilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRauscher JF, Morris JF, Fredericks WJ, Lopez-Guisa J, Balakrishnan C, Jost M, Herlyn M, Rodeck U. Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms; tumor suppressor protein. Hybridoma 1998; 17:191
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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