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Antigenic Specificity | PIP5K1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as actin cytoskeleton organization, cell adhesion, migration and phagocytosis. Required for membrane ruffling formation, actin organization and focal adhesion formation during directional cell migration by controlling integrin-induced transloca |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 231-500 of human PIP5K1A (NP 001129109.1). |
Other Names | [phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 4; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha] |
Gene, Accession # | [PIP5K1A], Gene ID: 8394, NCBI: NP_001129109, UniProt: Q99755 |
Catalog # | MBS8548976 |
Price | $280 |
Order / More Info | PIP5K1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |