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Antigenic Specificity | Human CD281 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human CD281 antibody detects an epitope within the N-terminal (NT) region of CD281, also known as toll like receptor 1 (TLR1). TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and serve as an important link between the innate and adaptive immune response through the production of cytokines. TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, and in particular triacylated lipoproteins. TLR1 can also regulate other TLR responses; TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response t |
Immunogen | Histology Positive Control Tissue: Mouse spleen. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to CD281 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [toll-like receptor 1; Toll-like receptor 1; toll-like receptor 1; toll/interleukin-1 receptor-like protein; toll-like receptor 1; Toll/interleukin-1 receptor-like protein; TIL; CD_antigen: CD281], [TLR1; TLR1; TIL; CD281; rsc786; TIL. LPRS5; KIAA0012; TIL] |
Gene, Accession # | [CD281], Gene ID: 7096, NCBI: NP_003254.2, UniProt: Q15399 |
Catalog # | MBS221470 |
Price | $375 |
Order / More Info | Human CD281 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |