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Antigenic Specificity | Cdc6 (Phospho Ser54) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Cdc6 (S54) Polyclonal Antibody detects endogenous levels of Cdc6 protein only when phosphorylated at S54. The protein encoded by CDC6 (cell division cycle 6) is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. |
Immunogen | Immunogen: Synthesized peptide derived from human Cdc6 around the phosphorylation site of S54 |
Other Names | [Rabbit Cdc6 (phospho Ser54); CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6] |
Gene, Accession # | [CDC6], Gene ID: 990, NCBI: NP_001245.1, UniProt: Q99741 |
Catalog # | MBS9707743 |
Price | $130, $220, $325 |
Order / More Info | Cdc6 (Phospho Ser54) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |