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Antigenic Specificity | FAAH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total FAAH protein. Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse (1). Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid (2). This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation (2). Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo (3). FAAH1 null mice also demonstrate an increased preference for alcohol and an incr |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human FAAH. |
Other Names | [FAAH; FAAH1; MGC102823; MGC138146] |
Gene, Accession # | [FAAH], Gene ID: 2166, NCBI: NP_001432.2, UniProt: O00519 |
Catalog # | MBS9405405 |
Price | $255 |
Order / More Info | FAAH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |