PKC delta/PRKCD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PKC delta/PRKCD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for PKC delta/PRKCD detection. Tested with WB, IHC-P, IHC-F, ICC, FCM, Direct ELISA in Human; Mouse; Rat.Background: Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene. The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. This gene is mapped to 3p21.1. Studies both in human and mice demonstrate that this kinase is involved inB cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. PRKCD is also regulated by phosphorylation on vario |
| Immunogen | Immunogen: E Coli-derived human PKC delta/PRKCD recombinant protein (Position: F4-D676). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P), IHC(F) and ICC. |
| Other Names | [Protein kinase C delta type; protein kinase C delta; Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta; Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit; Sphingosine-dependent protein kinase-1; SDK1; PRKCD] |
| Gene, Accession # | [PRKCD], Gene ID: 5580, NCBI: NP_006245.2, UniProt: Q05655 |
| Catalog # | MBS1752452 |
| Price | $315 |
| Order / More Info | PKC delta/PRKCD Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Qu, Y., Misaghi, S., Izrael-Tomasevic, A., Newton, K., Gilmour, L. L., Lamkanfi, M., Louie, S., Kayagaki, N., Liu, J., Komuves, L., Cupp, J. E., Arnott, D., Monack, D., Dixit, V. M.Phosphorylation of NLRC4 is critical for inflammasome activation. Nature 490: 539-542, 2012. 2. Salzer, E., Santos-Valente, E., Klaver, S., Ban, S. A., Emminger, W., Prengemann, N. K., Garncarz, W., Mullauer, L., Kain, R., Boztug, H., Heitger, A., Arbeiter, K., Eitelberger, F., Seidel, M. G., Holter, W., Pollak, A., Pickl, W. F., Forster-Waldl, E., Boztug, K. B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C-delta. Blood 121: 3112-3116, 2013. 3. Tu, X., Joeng, K. S., Nakayama, K. I., Nakayama, K., Rajagopal, J., Carroll, T. J., McMahon, A. P., Long, F. Noncanonical Wnt signaling through G protein-linked PKC-delta activation promotes bone formation. Dev. Cell 12: 113-127, 2007. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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