Edit |   |
---|---|
Antigenic Specificity | CD252 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: OX40L(TNFSF4) is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. Protein Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |
Immunogen | Immunogen: E Coli-derived mouse CD252 recombinant protein (Position: Q49-L198). Subcellular Localization: Membrane; Single-pass type II membrane protein. |
Other Names | [Tumor necrosis factor ligand superfamily member 4; OX40 ligand; OX40L; CD252; Tnfsf4; Ox40l; Txgp1l] |
Gene, Accession # | [CD252], Gene ID: 22164, NCBI: NP_033478.1, UniProt: P43488 |
Catalog # | MBS1750777 |
Price | $315 |
Order / More Info | CD252 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |