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Antigenic Specificity | Doublecortin/DCX |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | bovine, human, mouse, porcine, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Doublecortin (DCX) has a molecular weight of about 45kDa. The protein contains two domains, each about 90 amino acids long, which are believed to function in binding to microtubules, a C-terminal serine and proline rich region which may become phosphorylated in vivo. DCX is expressed very early in neuronal development, as neuroblasts become post-mitotic, but is lost as neurons mature. Developing neurons start to lose DCX expression about the time that they begin to express NeuN, a neuronal specific RNA binding protein characteristic of more mature neurons. Antibodies to DCX are used to identify stem cells in sections and in tissue culture, and to see if neurogenesis is taking place. |
Immunogen | Immunogen: Recombinant full length human Doublecortin purified from E Coli. |
Other Names | [doublecortin; Neuronal migration protein doublecortin; neuronal migration protein doublecortin; doublecortin; Doublin; Lissencephalin-X; Lis-X], [DCX; DCX; DC; DBCN; LISX; SCLH; XLIS; DBCN; LISX; Lis-X] |
Gene, Accession # | Gene ID: 1641, NCBI: AAC31696.1 |
Catalog # | MBS555045 |
Price | $405 |
Order / More Info | Doublecortin/DCX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |