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Antigenic Specificity | RPB7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RPB7 antibody detects endogenous levels of total RPB7. Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The |
Immunogen | Immunogen: A synthesized peptide derived from human RPB7 Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Xenopus (100%) |
Other Names | [DNA directed RNA polymerase II 19 kDa polypeptide; DNA directed RNA polymerase II subunit G; DNA directed RNA polymerase II subunit RPB7; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; hRPB19; hsRPB7; MGC138367; MGC138369; POLR2G; polymerase (RNA) II (DNA directed) polypeptide G; RNA polymerase II 19 kDa subunit; RNA polymerase II subunit B7; RPB19; RPB7; RPB7_HUMAN] |
Gene, Accession # | [RPB7], Gene ID: 5436, NCBI: NP_002687.1, UniProt: P62487 |
Catalog # | MBS9609775 |
Price | $240, $280 |
Order / More Info | RPB7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |