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Antigenic Specificity | CD3E (C-term), 154-182 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E. The protein encoded by this gene is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, andthe T-cell receptor alpha/beta and gamma/delta heterodimers, formsthe T-cell receptor-CD3 complex. This complex plays an importantrole in coupling antigen recognition to several intracellularsignal-transduction pathways. The genes encoding the epsilon, gammaand delta polypeptides are located in the same cluster onchromosome 11. The epsilon polypeptide plays an essential role inT-cell development. Defects in this gene cause immunodefi |
Immunogen | n/a |
Other Names | [T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; CD3E; T3E] |
Gene, Accession # | [CD3E], Gene ID: 916, NCBI: NP_000724.1, UniProt: P07766 |
Catalog # | MBS9206173 |
Price | $165, $370 |
Order / More Info | CD3E (C-term), 154-182 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Brophy, K., et al. BMC Med. Genet. 11, 76 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Su, Z., et al. Int. J. Mol. Med. 24(4):437-444(2009) |