CD3E (C-term), 154-182 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD3E (C-term), 154-182
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: monkey)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.35
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis CD3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E. The protein encoded by this gene is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, andthe T-cell receptor alpha/beta and gamma/delta heterodimers, formsthe T-cell receptor-CD3 complex. This complex plays an importantrole in coupling antigen recognition to several intracellularsignal-transduction pathways. The genes encoding the epsilon, gammaand delta polypeptides are located in the same cluster onchromosome 11. The epsilon polypeptide plays an essential role inT-cell development. Defects in this gene cause immunodefi
Immunogenn/a
Other Names[T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; CD3E; T3E]
Gene, Accession #[CD3E], Gene ID: 916, NCBI: NP_000724.1, UniProt: P07766
Catalog #MBS9206173
Price$165, $370
Order / More InfoCD3E (C-term), 154-182 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Brophy, K., et al. BMC Med. Genet. 11, 76 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Su, Z., et al. Int. J. Mol. Med. 24(4):437-444(2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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